The last time the two sides met, the Chairboys dumped Preston out of the FA Cup with a 4-1 hammering, and their league meeting at Deepdale back in December finished 2-2.
Speaking ahead of the game, Preston boss Alex Neil revealed he's already working on transfer plans for the summer, and claimed: "The recruitment side is going to be huge for us this summer. We are all aware we have got a massive rebuilding job which half started in January and is going to hopefully continue in the summer.
“We have a large number of loans at the moment and we will see what we can do with some of them. Equally, we have some other players out of contract in the summer.
“I would imagine, whether the loan lads stay or not, that it will be the biggest overhaul of the squad we have probably had in the summer.”
Here are today's biggest transfer stories and the latest team news involving Preston North End and the rest of the Championship, as the build-up to the upcoming weekend's action begins.
1. Race heats up for Delap
Stoke City and Bournemouth are both believed to be keeping tabs on Manchester City starlet Liam Delap. He looks set to head out on loan next season to gain more first-team experience. (Football League World)
Photo: Charlotte Tattersall
2. Canaries close in on ex-Boro man
Norwich City are moving closer to landing Burnley defender Ben Gibson on a permanent deal, with the move set to be confirmed if the Canaries clinch promotion. He joined the Clarets from Middlesbrough for £15m back in 2018. (The 72)
Photo: Michael Steele
3. Cook suffers season-ending injury
Bournemouth's push for promotion has taken a major blow, with star midfielder Lewis Cook set to miss the rest of the season after rupturing his ACL. He suffered the same injury on the same knee back in 2018. (The Athletic)
Photo: Naomi Baker
4. Swans boss tells side to ignore the hype
Swansea City boss Steve Cooper has urged his side to pay no attention to the hype surrounding his side, as they continue to push for automatic promotion. They're currently in 3rd place, level on points with 2nd place Watford. (BBC Sport)
Photo: Jan Kruger