The last time the two sides met, the Chairboys dumped Preston out of the FA Cup with a 4-1 hammering, and their league meeting at Deepdale back in December finished 2-2.
Speaking ahead of the game, Preston boss Alex Neil revealed he's already working on transfer plans for the summer, and claimed: "The recruitment side is going to be huge for us this summer. We are all aware we have got a massive rebuilding job which half started in January and is going to hopefully continue in the summer.
“We have a large number of loans at the moment and we will see what we can do with some of them. Equally, we have some other players out of contract in the summer.
“I would imagine, whether the loan lads stay or not, that it will be the biggest overhaul of the squad we have probably had in the summer.”
Here are today's biggest transfer stories and the latest team news involving Preston North End and the rest of the Championship, as the build-up to the upcoming weekend's action begins.
5. Norwich face competition for Skipp
A host of unnamed Premier League clubs are rumoured to be taking an interest in Spurs' Oliver Skipp, who is currently starring on loan with Norwich City. The Canaries are still hopeful of bringing him back to Carrow Road next season. (The 72) Photo: Shaun Botterill
6. Ex-Royal yet to join Salford
Ex-Reading man Noel Hunt was believed to have been on the verge of moving with Richie Wellens from Swindon Town to Salford City, only for the deal to fail to materialise. He's still out of work since leaving the Robins. (The Sun) Photo: Pete Norton
7. Whites forward could be moved on
Leeds United forward Tyler Roberts has been tipped by pundit Alex McLeish to leave the club this summer, suggesting the Whites will look to bring in "other targets" to replace him. He's previously been linked with Derby County. (Football Insider) Photo: MICHAEL REGAN
8. Hoyle slams ex-Owls boss' tactics
Ex-Huddersfield chairman Dean Hoyle has claimed Carlos Carvalhal's "risk averse" tactics played into the Terriers' hands in the 2016/17 play-off semi-finals, and ultimately cost Sheffield Wednesday a place at Wembley. (LGOP) Photo: Harry Trump