Preston North End make the lengthy trip down to the South Coast to face Southampton at St Mary's in the Sky Bet Championship.
The Lilywhites arrive in Hampshire on the back of a seven game unbeaten run, following their goalless draw with Hull City at the weekend. PNE couldn't narrow the gap on the play-offs, but they didn't lose any major ground either.
Southampton, meanwhile, got themselves back among the winning trail after back-to-back defeats against Hull City and Millwall. The Saints won 4-3 against Birmingham City, courtesy of Joe Aribo's strike in stoppage time.
Southampton are fourth and are still in contention for an automatic promotion spot, despite the good form of Ipswich Town and Leeds United. The two sides met at Deepdale back in October and it was Southampton who were perhaps the most fortunate.
Preston led through Milutin Osmajic and Brad Potts who scored in a three-minute salvo, after Kyle Walker-Peters' well placed opener. But, a Potts own goal in the sixth minute of additional time denied PNE the victory.
Neither side's injury list is too long, but there are players who will miss out. Southampton have invested heavily in their squad, but they're to be without one of their most expensive acquisitions, - who has been reduced to just two substitute outings this term. Here is the latest injury and team news ahead of kick-off on Wednesday night.
9. Ryan Fraser- out
Had to leave St Mary's on crutches against Millwall and will be out for a month with a knee injury. Martin said, on Tuesday: "Wee Man will be the same. The Leicester game being delayed suits him as he'll miss one game less. We’re hopeful he’ll be back for Middlesbrough. If he’s not it will be the game after." | Getty Images
10. Kyle Walker-Peters - doubt
Missed the win against Birmingham and is a doubt for this game too. | Getty Images
11. Kyle Walker-Peters - doubt (continued)
“He was back on the grass today, tomorrow may be too early," said Martin on Tuesday afternoon. "It probably will be. But we’re hopeful to have him back on Saturday.” | Getty Images