The crash occurred on the eastbound carriageway between junctions 3 (Brimmicroft Interchange) and 4 (Earcroft Interchange) this afternoon.
Eyewitnesses said the collision involved multiple vehicles, causing one to hit the central reservation.
One lane was closed and traffic officers were called to the scene, Highways England said.
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The lane reopened at around 4.50pm but congestion remains on the approach.
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