For some players it will be disappointment, for others it will be jubilation as they get the chance to play in a famous old fixture between their club and their nearest and fiercest rivals.
But who will Ryan Lowe pick for the game at Bloomfield Road?
5. LWB: Alvaro Fernandez
A player that is growing more and more his loan progresses, Alvaro Fernandez could provide some important energy and pace to the North End side. Photo: CameraSport - Alex Dodd
6. CB: Jordan Storey
After another good display in midweek, and with the back line already missing Liam Lindsay, Jordan Storey should continue on the right side of the back three. Photo: CameraSport - Alex Dodd
7. GK: Freddie Woodman
It's difficult to come up with another superlative to describe Freddie Woodman's start to life at PNE, after 10 clean sheets in 16 he'll be hoping for an 11th on Saturday. Photo: CameraSport - Alex Dodd
8. RWB: Brad Potts
Brad Potts was recently brought back into the side and is a reliably defensive option away from home, against his former club. Photo: CameraSport - Alex Dodd