It is the first meeting between the sides at Deepdale since August 2013 and the first in the league since 2010.
Here we are look at some past meetings which put a smile on the faces of North End supporters.
13. Celebration time
Michael Appleton and David Eyres celebrate PNE's third goal against Blackpool in December 1999 Photo: KEVIN McGUINNESS
14. Making himself a hero...
Tom Clarke heads home against Blackpool in August 2013 Photo: Kevin McGuinness
15. Late, late joy!
Tom Clarke celebrates with Paul Huntington after scoring PNE's winner against Blackpool in August 2013 Photo: Kevin McGuinness