Lindsay arrives at Deepdale on a loan until the end of the season, bolstering their thinning ranks of centre halves.
The 25-year-old started his career at Partick Thistle, going on to make 62 appearances for the club amongst a couple of loan spells still north of the border.
The Scot then moved south, joining Barnsley for a fee and helping the Tykes win promotion to the Championship.
Upon their promotion, Lindsay was bought by Stoke City in a deal worth £2m but has found game time hard to come by this season, despite making 23 appearances in the last campaign.
Speaking to the PNE website, Lindsay said: “It’s been pretty quick and I’m just happy to have it done and dusted and I’m looking forward to it.
“It is obviously a big attraction coming here and the gaffer wanted me here, which gives me confidence, so I’m just looking to get as many games as possible and help the team.”
PNE boss Alex Neil is pleased to bring in his countryman, with his acquisition coming out of preparation.
He said: “It is good to get this bit of business done. The Ben Davies one came out of the blue so it’s not something we expected, but he have obviously been keeping an eye on left sided centre backs in case that did happen.
“Liam is a guy who has played at the level, he’s been at Stoke, he’s been at Barnsley, he’s a good age, he’s left-sided and left footed and I think it makes sense to bring someone in who can hopefully do well between now and the end of the season.
“He’s a good presence, a good size, and we are really hopeful for him. He hasn’t played a lot of football this year and we want to make sure that he gets his season up and running.”