Daniel Johnson comes into the side to replace Ryan Ledson in midfield.
Johnson missed Satuerday's home defeat to Sheffield United because of an Achilles injury.
Ledson moves to the bench with Paul Gallagher dropping out of the matchday squad.
PNE: Rudd, Fisher, Storey, Davies, Earl, Pearson, Nmecha, Browne, Johnson, Robinson, Maguire. Subs: Moult, Rafferty, Ginnelly, Ledson, Stockley, Huntington, Crowe.
Leeds: Casilla, Ayling, Cooper, Jansson, Alioski, Phillips, Hernandez, Harrison, Klich, Roberts, Bamford. Subs: Forshaw, Roofe, Dallas, Berardi, Shackleton, Stevens, Peacock-Farrell.
Referee: Robert Jones (Merseyside)