North End have taken just one point from a possible nine but a win at Bramall Lane would firmly put them back on course for a top six spot.
Unfortunately for the Lilywhties, they do not historically travel well to United, but this weekend is a chance to change that.
One time that they did enjoy their trip to Yokrshire was in 2018, as Alex Neil’s side won 1-0, with Alan Browne scoring the only goal of the game.
The win meant North End’s hopes of a play-off place went to the final day of the season (sound familiar?) although they ended up finishing seventh.
5. Committed to the cause
Preston North End fans watch their team in action Photo: CameraSport - Chris Vaughan
6. Win in the bag
Callum Robinson celebrates PNE's win at Sheffield United on Saturday Photo: National World
7. Maguire has a go
Preston North End's Sean Maguire gets a shot in at goal under pressure from Sheffield United's Jack O'Connell Photo: CameraSport - Chris Vaughan
8. Gally takes off
Chris Basham of Sheffield Utd volleys in a shot with Paull Gallagher closing it down Photo: Simon Bellis