Heung-Min Son scored twice before Arnaut Danjuma made it three, with all goals coming in the second half.
There were over 21,000 fans in Deepdale for the blockbuster tie live on BBC One, and here are our best fan pictures from the evening.
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PNE fans at the game against Tottenham Photo: CameraSport - Dave Howarth
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PNE fans at the game against Tottenham Photo: CameraSport - Dave Howarth
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PNE fans at the game against Tottenham Photo: CameraSport - Dave Howarth
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PNE fans at the game against Tottenham Photo: CameraSport - Dave Howarth