The two teams are just outside the top seven in the National League North, but have a great opportunity to force their way into the promotion picture.
After beating AFC Telford United 2-1 at the weekend, the Magpies moved to within three points of seventh-placed York City, who were beaten by Harrogate Town.
Their hand was improved even further on Tuesday despite their game at Leamington being postponed due to the weather as York suffered another defeat – this time at Nuneaton Town.
Matt Jansen’s men have two games in hand on the Minstermen, but so do Blyth, who are one place and three points behind the Magpies. A win tomorrow for Chorley would put clear daylight between themselves and Blyth with four games of the league season left to play.
But a defeat would see them drawn back into the chasing pack, with a match at home to fifth-placed Stockport County to come on Tuesday.
“We have huge games against Blyth and Stockport County to come,” said Jansen.
“I am confident that we can make the play-offs, although that does not guarantee that we will do.
“The lads are full of confidence that they can and hopefully we will do.”
Jansen has bolstered his squad by recalling central defender Adam Anson from his loan spell with Lancaster City.
Chorley’s game against Leamington has been re-arranged for Thursday.