All eyes will be on cavernous Al Bayt Stadium on Sunday evening as the Group B winners play their first knockout match on the world stage since the agonising extra-time semi-final loss to Croatia in 2018.
England built on that performance by winning bronze at the following year’s Nations League before going on a memorable run to last year’s European Championship final at Wembley.
It’s now make or break in Qatar and the question on everyone’s lips is what team Southgate will pick.
Here is a ‘leaked’ England line-up based on various reports surrounding his selection for the clash with Senegal.
5. Luke Shaw
Kept his place as Southgate rotated against Wales and will continue his run of starts against Senegal. Photo: Mike Egerton
6. Jude Bellingham
He's only 19, but the Borussia Dortmund man is performing in a way that means Southgate can't even consider dropping him. All action in the middle of the park. Photo: Adam Davy
7. Declan Rice
With Kalvin Phillips only just coming back from injury, Rice had a clear path to be England's midfield anchor in Qatar and will continue the role against Senegal. Photo: Mike Egerton
8. Mason Mount
Not loved by all fans, but reports suggest Southgate will turn to a man he has trusted in plenty of recent big games with the Chelsea man likely to get the nod in the middle of the park. Photo: Mike Egerton