A road used over the years by motorists to avoid the Broughton roundabout is being closed for another 10 months.
A road closure order will be in place on D'Urton Lane from Monday, January 7 to Friday, November 8.
The closure, issued by Lancashire County Council, is in place 130 metres west of Highrigg Drive for a new roundabout to be created between D'Urton Lane and Eastway.
It is part of planning permission requirements that were approved by Preston Council for Story Homes' D'Urton Manor housing development.
The road has been a key link for motorists travelling from Preston, providing an alternative route to James Towers Way instead of heading to the congested Broughton roundabout at junction one of the M55.
Rina Housbey, principal design engineer for Lancashire County Council, said: "This is the start of work to create a new roundabout for a link road between D'Urton Lane and Eastway.
"We're carrying out this work on D'Urton Lane, which is developer-funded as part of the planning permission for the Story Homes development.
"The link road will help to reduce congestion in this area and provide access to new developments."
The daily closures will be in place from 7.30am to 6pm.
In February 2017 the road was closed off on the Eastway side for sewers to be built for a Persimmon Homes development in Highrigg.
A month earlier the A6 end of the road was closed for Electricity North West to carry out work in the road.
Ms Housbey added: "The work along D'Urton Lane includes diverting a culvert, moving utility services, street lighting work, and a temporary diversion for cyclists and pedestrians to maintain the Guild Wheel route.
"We've informed residents of this work, and we'll do what we can to minimise the impact for people who live there, while this work takes place."