The incident occurred on the southbound carriageway between junctions 25 (Bryn Interchange) and 26 (Orrell Interchange) at approximately 3.20pm.
Highways England described the collision as "minor" but warned motorists to expect 30 minute delays on the approach.
Traffic officers and recovery vehicles were called to the scene and the lane closures were lifted at around 5.45pm.
The collision involved a lorry and a car, according to the AA.
It is thanks to our loyal readers that we can continue to provide the trusted news, analysis and insight that matters to you.
For unlimited access to our unrivalled local reporting, you can take out a subscription HERE and help support the work of our dedicated team of reporters.