The accident happened at around 9.50am at the junction of Button Street and Inglewhite Road.
A police spokesman said: "There was a crash involving a lorry and a car this morning.
"A 17-year-old was injured and it appears that they hit the windscreen during the accident.
"The road was closed while the lorry was recovered."
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The vehicle has now been recovered although the road still remains closed.
The injured teen was taken to Royal Preston Hospital with minor injuries, say the ambulance service.