Northern have issued a statement confirming that the line between the stations has been blocked by a broken down train at Staveley station.
The company warned passengers that train services running to and from these stations may be cancelled, delayed by up to 30 minutes or revised.
The distruption is currently expected until midday.
Replacement bus serrvices are in operation between Oxenholme and Staveley in both directions.
Northern have asked that passengers on station platforms should listen for announcements or consult Customer Information Screens for travel updates.
Alternatively you can visit: northernrailway.co.uk/stations
If you have been delayed by 15 minutes or more, hold onto your tickets and claim compensation by visiting northernrailway.co.uk/delayrepay