Simon Day (54) was last seen at an address in Oakdale Drive on Wednesday, and it is thought he left there the following day. He has not returned since.
Officers are extremely concerned for his welfare and are urging anybody who knows of his whereabouts to contact them as soon as possible.
Simon is described as 6ft. 2in. tall, with a slim but muscly build, and grey hair. He may be wearing a dark blue jacket with bits of orange and blue Adidas trainers.
He has links to Clitheroe, Leyland, Horwich, Preston, Horwich and Stoke-on-Trent.
For immediate sightings of Simon, ring 999. For anybody who may have seen him or know anything about where he may be, call 101 quoting reference 1236 of November 27th