Traffic has been redirected from junction nine of the M61, with congestion around the M65 and leading up to junction 30 near Preston as Lancashire Road Police attend to a number of incidents along the route.
Police have confirmed there are no serious injuries but had taken time to ensure everyone's safety at the scene.
Travellers have taken to social media to talk of delays of up to two hours as roads came to a standstill,. It understood more than 20 vehicles were involved in separate incidents folllowing a heavy burst of wintry showers just before 4pm today (December 27)
M6 reopens after vehicle transporting sheep overturns following crash between Preston and Lancaster
Lewis Turner inquest: moped rider "travelling at motorway speeds" on residential New Longton road and without fastened helmet before fatal crash
Preston Brick Veil Mosque inquiry closes as debate rages over whether the place of worship should be permitted
The Old Vicarage Care Home: special measures status for Lancashire care home where resident was left lying on floor after falling out of bed
M65 motorway crews strimming verges until 4am keep residents awake at night
Northwest Motorway Police issued a statement this evening reminding people in the county only to make journeys on the roads for 'essential travel.'
A spokesperson said: "Its a very wintry evening, there are numerous incidents up in the Lancashire area due to the weather please bear this in mind, if you are having to to make essential travel."
Highways England North West posted on their Twitter account at 7.40pm that the M6 junction 28 northbound was fully open.
Andrew Jardine, who is travelling on the M6 this evening posted on the platform that he had now been stuck at a standstill for more than two hours.
One eye-witness alleged to having seen one vehicle hit three times after skidding in the fast lane just after junction 29.
The Met Office earlier this afternoon had issued a yellow weather warning for the north west, with forecasters predicting snow and ice showers in the Lancashire area overnight.
Lancashire Road Police have issued a statement asking all motorists to take extra care if having to travel through the evening and to adjust their driving due to the inclement weather conditions.