St Teresa’s in Fishwick was closed in 2011 after the Diocese of Lancaster amalgamated a number of parishes due to falling congregation figures.
The three-storey care home bid – submitted by Yorkshire-based Exemplar Healthcare – will create up to 90 jobs.
Documents set to be discussed by the city council’s planning committee tomorrow say the Church Avenue red-brick structure is not a listed building and not designated as a community asset.
The parish hall – which is included in the demolition plan – has been vacant since 2013.
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If approved by the committee, the 30-bed care facility will provide accommodation for adults who require 24-hour care for a range of complex medical conditions.
The application has been recommended for approval by council officers but needs to be given the green light by members of the planning committee.