Two fire engines from Preston and Penwortham attended the scene in Langton Street at around 1.40am today (September 14).
The incident involved a fire in the living room of a domestic property that was well alight when crews arrived.
Firefighters used one breathing apparatus, one hose reel, and one positive pressure unit to extinguish the flames.
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One casualty was given first aid, the fire service said.
Crews were at the scene for approximately two hours and 40 minutes.
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