The conference will take place tomorrow (Thursday May 27) and will be hosted by the University of Central Lancashire (UCLan).
Academics will gather online to study the rock legends and the innovative event has backing from Arts Council England.
Special guests will attend to share unique insights into the band and present a selection of academic papers.
Back to school: How expensive are secondary school uniforms in Preston?
Lancashire students anxiously waiting for exam results urged to seek support from Talkzone
GCSE results: Painting and Decorating Assocation puts out call to Chorley and Leyland school leavers
How UCLan’s latest pet project - a new vets’ school in Preston – would help solve acute shortage of animal doctors in UK
‘I want to help and inspire others’: Lancashire educational mentoring scheme changing kids’ lives
One prominent guest is Tim Staffell, the 'Smile' lead vocalist and bassist who, alongside Brian May and Roger Taylor, provided the basis from which Queen evolved.
Staffell's departure from Smile to join band 'Humpy Bong' featured in 2018 Queen biopic 'Bohemian Rhapsody'. It is believed that this departure paved the way for Freddie Mercury, and later John Deacon, to come together as Queen.
Co-organsier Tony Rigg a music industry consultant, said: “Clearly Queen have had a long and remarkable career.
"The band is arguably more popular now than ever before, so we’ll be discussing how this legacy was created and how others could possibly follow in their footsteps.
"These topics and many more will be debated in what we think is the world's first academic conference dedicated to the study of Queen."
Mr Rigg, who helped to establish UCLan’s Master of Arts programme in music industry management, said that all are welcome at the virtual conference.
“Although it’s billed as an academic conference, anyone with an interest in Queen is welcome to watch," he said.
"There is much to explore and while we can only really scratch the surface, I’m confident we will uncover some valuable insights.”
Other speakers include guitar expert Phil Hilborne who, amongst other Queen-related activities, was one of the guitarists from Queen musical 'We Will Rock You'.
Additional insight will be provided by Simon Bradley, who collaborated with Brian May to write a book dedicated to the instrument known as the Red Special; a guitar that Brian May built with his father which became a key element of Queen's distinctive sound.
The two part conference will see academic papers presented in the first half followed by interviews with special guests.
The conference will be available to watch live on YouTube, giving audience members a chance to ask questions through the comments section.
Thanks for reading. If you value what we do and are able to support us, a digital subscription is just £1 per month for the first two months. Try us today by clicking here.