Gym Works has been given planning permission to open a new site on Pittman Way, Fulwood.
Owners say it is hoping to attract customers from the many businesses situated in the northern Preston employment area.
The firm, which already has a site in Euxton, near Chorley, is hoping to open in Preston in the next couple of months.
A spokesman said: “Gym Works is a ground breaking, premium fitness club is opening late summer 2017.”
The building is 20,000 sq/ft and will be next to JTF Discount Warehouse, on Pittman Way, Fulwood.”
The gym is aiming at the low-cost market, and says it has cut costs by not having a swimming pool, sauna or steam room.
But it has a full fitness suite with a wide range of gym and fitness equipment.