The yellow weather warning for rain covers Lancaster, Clitheroe, Burnley, Longridge and Bacup.
It will be active between 2am and 11.59pm on Tuesday, October 5.
Forecasters said 15-30mm of rain is expected to fall, bringing the risk of localised flooding and difficult driving conditions.
A spokesman for the Met Office added: "Rain, accompanied with strengthening winds, will move north and eastwards across the area early on Tuesday, becoming slow-moving over parts of northeast England and, later, also eastern England. 15-30 mm of rain is expected to fall quite widely.
"Over eastern and northeastern England, 40-50 mm of rain is likely to fall in some parts with 50-75 mm also possible in a few spots."
Here's what to expect:
- A few homes and businesses flooded
- Bus and train services affected with journey times taking longer
- Spray and flooding on roads will make journey times longer
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