An ambulance and two police cars were called to the collision on the A584 Preston New Road, near the Lea Gate pub, at around 1.15pm today (November 18).
The white van, which reportedly became embedded in woodland on the westbound carriageway, was badly damaged and its airbags had deployed, according to eyewitnesses.
Police say they believe it was a minor injury collision.
"The only incident I can find is a minor injury RTC so we wouldn't give any more information," a spokesman for Lancashire Police said.
North West Ambulance Service have been approached for comment.
Support us and become a subscriber today. Enjoy unlimited access to local news, the latest football stories and new puzzles every day. With a digital subscription, you can see fewer ads, enjoy faster load times, and get access to exclusive newsletters and content. Click here to subscribe.