Drivers travelling on the M65 have been warned to expect delays following a four-vehicle smash, say Highways England.
The accident happened at around 8:40am on Tuesday on the westbound carriageway between junctions 7 and 6 in Blackburn.
Highways England say that all lanes have re-opened and delays are clearing.
Lancashire Fire and Rescue have are attending the incident.
Nobody is believed to have been injured in the incident.