Four children and a man have been taken to hospital after a fire at a house in Manchester.
Firefighters were called to the blaze in Withington, Manchester, at about 2.20am on this morning.
A spokesman for Greater Manchester Police said three girls and one boy aged between 10 and 17 were taken to hospital where they are being treated for their injuries.
A man was also taken to hospital and he remains in a serious condition.
Superintendent Mark Kenny of GMP said: “This is a tragic incident and we are working work closely with GMFRS to establish exactly how this fire started.
“We want to speak to anyone who may have witnessed the fire, or were in the area in the hours before the fire.
“If you have any information I urge you to contact police as soon as possible so we can piece together what happened.”
Four fire engines were called to the scene in Parsonage Road, along with police and ambulances.
The cause of the blaze is due to be investigated jointly with Greater Manchester Police.
Anyone with information is asked to contact police on 101 quoting incident number 140 10/02/17 or the independent charity Crimestoppers, anonymously, on 0800 555 111.