Police believe a group of young men had been riding in the area when one of the bikes collided with a red Toyota Yaris car in Harold Street at around 12.55pm today (December 23).
The motorcyclist, a 22-year-old man, was pronounced dead at the scene shortly after emergency services arrived and found him with "serious injuries".
The rest of the convoy made off from the scene and when officers attended the motorbike had also been removed from the area.
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Police are now urging anyone with any information about the bike's whereabouts to "search their conscience" and tell officers where they can find it so they can conduct a thorough investigation.
Sgt Andy Halliwell, of the Lancashire Police TacOps team, said: "This was an utterly tragic incident, with a 22-year-old man having lost this life. First and foremost our thoughts are with his family and friends and we send them our deepest condolences.
"We are now urging anybody with information about where the motorbike is to get in touch. It is a key piece of evidence and we need to get it back in order to carry out a full, thorough investigation. If you have any information at all about where it is, or who may have it, please tell us.
"We are also asking anybody who witnessed the collision and has not yet been spoken to by police, or anyone who has dashcam or CCTV showing the collision, to contact us."
Anybody with information has been urged to contact police by calling 101, quoting log number 667 of December 23.
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