Leyland were pushed all the way by Northern League newcomers Penrith before emerging from their Fox Lane clash victorious.
David Makinson won the toss and asked the Cumbrians to bat first, a decent shout with his side going on to bowl out Penrith for 116.
Karl Cross returned good figures of 4-33, while Daniel Lamb and Tayyab Afsar both took two wickets.
Lamb went on to perform well with the bat, the opener scoring 38.
There was a knock of 24 from Andrew Makinson but Leyland were down to their last pair before clinching the victory.
Chorley recorded a big win over Blackpool at Windsor Park, with Billy Smith in fine form with the ball.
Smith returned impressive figures of 7-26 as the visitors were dismissed for just 67 when replying to the target set for them by Chorley.
The home side had won the toss and elected to bat first.
They were 154-9 in their 50 overs, opening pair David Fisher and Andrew Winrow solid with knocks of 29 and 20 respectively.
Further down the order, Gaurav Dhar top scored with 46.
Blackpool started their reply well but openers Richard Gleeson (28) and Matthew Houston (18) were the only visiting players to reach double figures.
Smith cut through their order with his seven wickets, while Chris Harty took 2-15.
Preston and Barrow fought out a high-scoring draw at West Cliff.
Asked to bat first, Barrow declared at 204-8 in the 42nd over. There was a decent chase from Preston before they closed on 192-8.
Morecambe were well beaten at home by Darwen, the visitors winning by 79 runs.
Darwen elected to bat first and put 166-9 on the board, George Linde hitting 66.
In reply, Morecambe were dismissed for 87. Kelly Smuts top scored with 20, while Ryan Pearson was unbeaten on 16.
Lancaster returned empty-handed from their visit to Netherfield, losing by eight wickets. Batting first, they were 128 all out, Michael Barry the pick of the batsmen with 32.
Netherfield replied with 130-2 to claim victory.
Jean De Villiers hit a ton as Fleetwood enjoyed a fine away day at St Annes.
The South African pro clubbed 101 off just 70 balls, hitting eight sixes and eight fours. Adam Parker was three runs short of a century as Fleetwood were 258-8.
St Annes were 150 all out in reply.