Former Preston North End boss Paul Simpson left Lancashire empty-handed after Morecambe ended Shrewsbury's unbeaten start to the season.
Rene Howe's fourth minute strike was enough to topple Simpson's heavyweights at Christie Park.
Howe stroked home from 12 yards from Stuart Drummond's pass to seal a welcome three points for Sammy McIlroy's men.
Howe came close to doubling the lead on 37 minutes but saw his shot tipped round the post by Luke Daniels.
Morecambe had the better of the chances in the second-half as the previous league leaders failed to seriously threaten Barry Roche's goal.
The game was only passed fit at 10am on Saturday morning after heavy rain threatened the kick-off.
Morecambe: Roche, McCann, Artell, Bentley, Parrish, Wainwright, Hunter, Drummond, Curtis, O'Carroll, Howe.
Subs: Davies, Stanley, McLachlan, Blinkhorn, McStay

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