Motorists are being held up in long queues after a smash on the M6 southbound near Preston.
Emergency services were called to an accident between a Ford Fiesta and a large goods vehicle between junctions 31 and 30 just before 6am.
Lanes were blocked to allow for vehicle recovery and to clear the area of debris.
Traffic was flowing again by 7.15am, but, congestion has built up because of the earlier closures.
Police said there were no injuries reported.