Rail passengers are experiencing delays after a freight train on its way to Lancashire derailed and caught fire.
The empty train was travelling through Manchester at around 2.30pm when it left the tracks.
It was heading from Ardwick to Carnforth, near Lancaster. The driver was uninjured.
Network Rail reported major disruption to services with trains to Preston affected.
A spokesman for Network Rail said: “At 2.34pm today we received a report of a derailment of an empty train between Salford Crescent and Deansgate stations in Manchester.
“The service, an empty charter service (two class 47 diesel locomotives and five coaches) operated by West Coast Railways, was travelling from Ardwick to Carnforth. The driver of the train is uninjured.
“Our response teams are currently on site and are assisting both the British Transport Police and the Rail Accident Investigation Branch as they look to determine the circumstances surrounding this incident.
“Trains are currently unable to run between Salford Crescent/Eccles and Manchester Piccadilly/Manchester Victoria. Passengers are advised to check with their train operator or National Rail Enquiries for the latest information on alternative travel arrangements.”