The southbound M6 motorway near Preston has been fully re-opened after being shut for eight hours.
Sgt Sean Cunningham, of the Road Policing Unit at Lancashire Police, said a lorry, carrying a load of frozen chicken, had flipped on its side blocking the entire carriageway at 9.40am on Tuesday.
It was thought the closure would stay in place until after rush hour.
But recovery vehicles took away the HGV and cleared the carriageway of the load of poultry.
It was fully re-opened at around 5.30pm.
One lane of the northbound carriageway which was closed re-opened earlier.
The 40-tonne lorry carrying a load of fresh chicken overturned after braking heavily after colliding with a BMW One Series car between Junction 29 at Bamber Bridge and Junction 28 at Leyland at 9.40am on Tuesday.
The driver of both vehicles escaped with “minor injuries” and up to 600 vehicles were trapped behind the accident for hours.
He said it appeared the lorry driver had lost control of his vehicle after braking heavily, turning the lorry onto its side.
A Highways Agency spokesman confirmed the lorry had damaged the central reservation and left part of barrier sticking into the northbound carriageway.
He added: “Traffic caught behind the accident was turned around onto the slip road and then onto the M61 and M65 motorways.
“A diversion has been set up to direct traffic onto the A6 and other surrounding roads.”
At 1pm, police reported that traffic was “light” on both carriageways of the M6 although roads around Leyland and Bamber Bridge are busy.
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